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Saturday, October 6, 2012

West Nile Virus On Rise. Deaths. States. CDC Data.

West Nile virus

From Wikipedia, the free encyclopedia
West Nile Virus
Virus classification
Group:Group IV ((+)ssRNA)
Family:Flaviviridae
Genus:Flavivirus
Species:West Nile virus
West Nile virus (WNV) is a mosquito-borne zoonotic arbovirus belonging to the genus Flavivirus in the family Flaviviridae. This flavivirus is found in temperate and tropical regions of the world. It was first identified in the West Nile subregion in the East African nation of Uganda in 1937. Prior to the mid 1990s, WNV disease occurred only sporadically and was considered a minor risk for humans, until an outbreak in Algeria in 1994, with cases of WNV-caused encephalitis, and the first large outbreak in Romania in 1996, with a high number of cases with neuroinvasive disease. WNV has now spread globally, with the first case in the Western Hemisphere being identified in New York City in 1999;[1] over the next 5 years, the virus spread across the continental United States, north into Canada, and southward into the Caribbean Islands and Latin America. WNV also spread to Europe, beyond the Mediterranean Basin [a new strain of the virus was recently (2012) identified in Italy]. WNV is now considered to be an endemic pathogen in Africa, Asia, Australia, the Middle East, Europe and in the United States, which in 2012 has experienced one of its worst epidemics.

Scientists crack secret of mosquito's immunity

The main mode of WNV transmission is via various species of mosquitoes which are the prime vector, with birds being the most commonly infected animal and serving as the prime reservoir host - especially passerines which are of the largest order (Passeriformes) of birds. WNV has been found in various species of ticks, but current research suggests they are not important vectors of the virus. WNV also infects various mammal species, including humans, and has been identified in reptilian species, including alligators and crocodiles, and also in amphibians. Not all animal species which are susceptible to WNV infection – humans included, and not all bird species develop sufficient viral levels to transmit the disease to uninfected mosquitoes, and are thus not considered major factors in WNV transmission.[2][3]
Approximately 80% of West Nile virus infections in humans are subclinical, which cause no symptoms.[4] In the cases where symptoms do occur – termed West Nile fever in cases without neurological disease – the time from infection to the appearance of symptoms (incubation period) is typically between 2 and 15 days. Symptoms may include fever, headaches, fatigue, muscle pain or aches, malaise, nausea, anorexia, vomiting, myalgias and rash. Less than 1% of the cases are severe and result in neurological disease when the central nervous system is affected. People of advanced age, the very young, or those with immunosuppression, either medically induced, such as those taking immunosupressive drugs, or due to a pre-existing medical condition such as HIV infection, are most susceptible. The specific neurological diseases which may occur are West Nile encephalitis, which causes inflammation of the brain, West Nile meningitis, which causes inflammation of the meninges which are the protective membranes that cover the brain and spinal cord, West Nile meningoencephalitis, which causes inflammation of the brain and also the meninges surrounding it, and West Nile poliomyelitis - spinal cord inflammation which results in a syndrome similar to polio, which may cause acute flaccid paralysis.
Currently, no vaccine against WNV infection is available. The best method to reduce the rates of WNV infection is mosquito control on the part of municipalities, businesses and individual citizens to reduce breeding populations of mosquitoes in public, commercial and private areas via various means including eliminating standing pools of water where mosquitoes breed, such as in old tires, buckets, disused swimming pools, etc. On an individual basis, the use of personal protective measures to avoid being bitten by an infected mosquito, via the use of mosquito repellent, window screens, avoiding areas where mosquitoes are more prone to congregate, such as near marshes, areas with heavy vegetation etc., and being more vigilant from dusk to dawn when mosquitoes are most active offers the best defense. In the event of being bitten by an infected mosquito, familiarity of the symptoms of WNV on the part of laypersons, physicians and allied health professionals affords the best chance of receiving timely medical treatment which may aid in reducing associated possible complications and also appropriate palliative care.

2012 West Nile virus update: October 2

As of October 2, 2012, 48 states have reported West Nile virus infections in people, birds, or mosquitoes. A total of 3,969 cases of West Nile virus disease in people, including 163 deaths, have been reported to CDC. Of these, 2,010 (51%) were classified as neuroinvasive disease (such as meningitis or encephalitis) and 1,959 (49%) were classified as non-neuroinvasive disease.
The 3,969 cases reported thus far in 2012 is the highest number of West Nile virus disease cases reported to CDC through the first week in October since 2003. Almost 70 percent of the cases have been reported from eight states (Texas, California, Louisiana, Mississippi, South Dakota, Michigan, Oklahoma, and Illinois) and a third of all cases have been reported from Texas.

West Nile Virus (WNV) Human Infections Reported to ArboNET, by
State, United States, 2012 (as of October 2, 2012)

Human Disease Cases Reported To CDC
StateNeuroinvasive Disease CasesNon–Neuroinvasive Disease CasesTotal Cases*DeathsPresumptive Viremic Blood
Donors†
Totals2,0101,9593,969163508
Alabama2473110
Arizona402767123
Arkansas37145164
California121952161041
Colorado505610630
Connecticut881601
Delaware15610
District Of Columbia20210
Florida35134824
Georgia271845411
Idaho381102
Illinois10845153516
Indiana125062614
Iowa6131906
Kansas15173210
Kentucky42603
Louisiana1071062131131
Maryland181735312
Massachusetts1552010
Michigan127511781036
Minnesota323466131
Mississippi88114202520
Missouri1041418
Montana05500
Nebraska176885122
Nevada51611
New Hampshire10100
New Jersey16193524
New Mexico19173616
New York452873412
North Carolina60622
North Dakota324577017
Ohio603797414
Oklahoma9072162935
Oregon03300
Pennsylvania1572214
Rhode Island22400
South Carolina16824311
South Dakota58137195342
Tennessee16102601
Texas67476414385458
Utah12300
Vermont10100
Virginia1181922
Washington31400
West Virginia30300
Wisconsin261238313
Wyoming34701
* Includes confirmed and probable cases.
†Of the 508 presumptive viremic blood donors, 76 (15%) developed clinical illness and are also included as "Human disease cases reported to CDC".

West Nile virus (WNV) activity reported to ArboNET, by state, United States, 2012 (as of October 2, 2012)

Map of West Nile Virus activity describing United States that describes No WNV activity, Any WNV activity, WNV human disease case or presumptive viremic blood donor information.
Footnote: The map displays white areas that represent no WNV activity reported, light green areas that represent any WNV activity* , dark green circles that represent disease cases, and dark green triangles that represent presumptive viremic blood donors.
* Includes WNV human disease cases, presumptive viremic blood donors, veterinary disease cases and infections in mosquitoes, birds, and sentinel animals.
† Presumptive viremic blood donors have a positive screening test which has not necessarily been confirmed.
Map shows the distribution of WNV activity* (shaded in light green), human infections (dark green circles), and presumptive viremic blood donors (dark green triangles) occurring during 2012 by state. If West Nile virus infection is reported from any area of a state, that entire state is shaded.

Data table:

Non-human West Nile virus infections have been reported to CDC ArboNET from the following states:
Alabama, Arizona, Arkansas, California, Colorado, Connecticut, Delaware, Florida, Georgia, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Montana, Nebraska, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Carolina, South Dakota, Tennessee, Texas, Utah, Vermont, Virginia, Washington, West Virginia, Wisconsin and Wyoming.
Four thousand four hundred and one human West Nile virus infections have been reported to CDC ArboNET from Alabama, Arizona, Arkansas, California, Colorado, Connecticut, Delaware, District of Columbia, Florida, Georgia, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Montana, Nebraska, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Carolina, South Dakota, Tennessee, Texas, Utah, Vermont, Virginia, Washington, West Virginia, Wisconsin, and Wyoming.

For information on WNV activity in Canada please see:http://www.phac-aspc.gc.ca/wnv-vwn/index.html

What Is West Nile Virus?

West Nile virus (WNV) is a potentially serious illness. Experts believe WNV is established as a seasonal epidemic in North America that flares up in the summer and continues into the fall. This fact sheet contains important information that can help you recognize and prevent West Nile virus.

What Can I Do to Prevent WNV?

New! Prevention measures consist of community-based mosquito control programs that are able to reduce vector populations, personal protection measures to reduce the likelihood of being bitten by infected mosquitoes, and the underlying surveillance programs that characterize spatial/temporal patterns in risk that allow health and vector control agencies to target their interventions and resources.
The easiest and best way to avoid WNV is to prevent mosquito bites.
  • When you are outdoors, use insect repellent containing an EPA-registered active ingredient. Follow the directions on the package.
  • Many mosquitoes are most active at dusk and dawn. Be sure to use insect repellent and wear long sleeves and pants at these times or consider staying indoors during these hours.
  • Make sure you have good screens on your windows and doors to keep mosquitoes out.
  • Get rid of mosquito breeding sites by emptying standing water from flower pots, buckets and barrels. Change the water in pet dishes and replace the water in bird baths weekly. Drill holes in tire swings so water drains out. Keep children's wading pools empty and on their sides when they aren't being used.

What Are the Symptoms of WNV?

  • Serious Symptoms in a Few People. About one in 150 people infected with WNV will develop severe illness. The severe symptoms can include high fever, headache, neck stiffness, stupor, disorientation, coma, tremors, convulsions, muscle weakness, vision loss, numbness and paralysis. These symptoms may last several weeks, and neurological effects may be permanent.
  • Milder Symptoms in Some People. Up to 20 percent of the people who become infected have symptoms such as fever, headache, and body aches, nausea, vomiting, and sometimes swollen lymph glands or a skin rash on the chest, stomach and back. Symptoms can last for as short as a few days, though even healthy people have become sick for several weeks.
  • No Symptoms in Most People. Approximately 80 percent of people (about 4 out of 5) who are infected with WNV will not show any symptoms at all.

How Does West Nile Virus Spread?

  • Infected Mosquitoes. Most often, WNV is spread by the bite of an infected mosquito. Mosquitoes become infected when they feed on infected birds. Infected mosquitoes can then spread WNV to humans and other animals when they bite.
  • Transfusions, Transplants, and Mother-to-Child. In a very small number of cases, WNV also has been spread through blood transfusions, organ transplants, breastfeeding and even during pregnancy from mother to baby.
  • Not through touching. WNV is not spread through casual contact such as touching or kissing a person with the virus.

How Soon Do Infected People Get Sick?

People typically develop symptoms between 3 and 14 days after they are bitten by the infected mosquito.

How Is WNV Infection Treated?

There is no specific treatment for WNV infection. In cases with milder symptoms, people experience symptoms such as fever and aches that pass on their own, although even healthy people have become sick for several weeks. In more severe cases, people usually need to go to the hospital where they can receive supportive treatment including intravenous fluids, help with breathing and nursing care.

What Should I Do if I Think I Have WNV?

Milder WNV illness improves on its own, and people do not necessarily need to seek medical attention for this infection though they may choose to do so. If you develop symptoms of severe WNV illness, such as unusually severe headaches or confusion, seek medical attention immediately. Severe WNV illness usually requires hospitalization. Pregnant women and nursing mothers are encouraged to talk to their doctor if they develop symptoms that could be WNV.

What Is the Risk of Getting Sick from WNV?

People over 50 at higher risk to get severe illness.People over the age of 50 are more likely to develop serious symptoms of WNV if they do get sick and should take special care to avoid mosquito bites.
Being outside means you're at risk. The more time you're outdoors, the more time you could be bitten by an infected mosquito. Pay attention to avoiding mosquito bites if you spend a lot of time outside, either working or playing.
Risk through medical procedures is very low. All donated blood is checked for WNV before being used. The risk of getting WNV through blood transfusions and organ transplants is very small, and should not prevent people who need surgery from having it. If you have concerns, talk to your doctor.

Pregnancy and nursing do not increase risk of becoming infected with WNV.

The risk that WNV may present to a fetus or an infant infected through breastmilk is still being evaluated. Talk with your care provider if you have concerns.

What Is the CDC Doing About WNV?

CDC is working with state and local health departments and other government agencies, as well as private industry, to prepare for and prevent new cases of WNV.
Some things CDC is doing include:
  • Manage and maintain ArboNET, a nation-wide electronic surveillance system where states share information about WNV and other arboviral diseases
  • Support states develop and carry out improved mosquito prevention and control programs
  • Developing better, faster tests to detect and diagnose WNV
  • Prepare updated prevention and surveillance information for the media, the public, and health professionals
  • Working with partners on the development of vaccines

What Else Should I Know?

If you find a dead bird: Don't handle the body with your bare hands. Contact your local health department for instructions on reporting and disposing of the body. They may tell you to dispose of the bird after they log your report.
For more information Call 1-800-CDC-INFO (1-800-232-4636), Monday - Friday, 8am-8pm ET, Closed Holidays Email cdcinfo@cdc.gov. (For TTY, call 1-888-232-6348.)



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